IndraLab

Statements

reach
"Altogether, these results indicate that USP11 is a KLF4‐specific deubiquitinase that promotes KLF4 degradation.3.3 USP11 mediates cancer cell proliferation and tumorigenesis by promoting KLF4 instability."
34114341
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"Functionally, USP11 mediated melanoma cell proliferation via the regulation of NONO levels because ablation of USP11 inhibits the proliferation which could be rescued by ectopic expression of NONO protein."
33369124
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"Physiologically, USP11 depletion suppresses cell proliferation and wound healing in lung epithelial cells, and these effects are reversed by E2F1 and PEG10 overexpression."
28992046
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"USP11 depletion decreases DLBCL cell proliferation."
29483509
reach
"Ablation of USP11 or RAE1 reduces cell proliferation of U2OS cells."
29293652
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"Our observation that depletion of USP11 or inhibition using a non specific inhibitor such as Mitoxantrone significantly reduces DLBCL proliferation further supports the need for the development of USP11 specific inhibitors for targeting DLBCL."
29483509
reach
"Functionally, USP11 mediated stabilization of p21 inhibits cell proliferation and tumorigenesis in vivo."
29666278