IndraLab

Statements

CYLD inhibits CASP8. 3 / 3
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"Moreover, down-regulated CYLD expression also significantly suppressed caspase 8 activation."
28633009
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"Consistent with the data above, silencing CYLD largely abolished caspase 8 activation and necroptotic cell death induced by 5z-7 plus TNFalpha (XREF_FIG)."
27685625
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"As shown in XREF_FIG, upon selenite treatment, cIAPs were degraded, and CYLD transcription was upregulated, causing degradation of RIP1 K63 ubiquitin chains and subsequent DISC formation, caspase-8 activation and apoptosis."
24577083