IndraLab

Statements

USP3 binds POU5F1. 7 / 7
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sparser
"USP3 interacts with endogenous Oct4 and co-localizes in the nucleus of hESCs."
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sparser
"USP3 Interacted with Oct4."
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sparser
"For this purpose, we performed immunoprecipitation (IP) experiments to investigate the interaction between USP3 and Oct4 at the exogenous level."
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sparser
"IP using endogenous USP3 antibody resulted in precipitation of endogenous Oct4 in NCCIT cells ( xref C) as well as in hiPSCs ( xref D), indicating that USP3 interacts stably with endogenous Oct4 in stem cells."
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reach
"USP3 interacts with endogenous Oct4 and co-localizes in the nucleus of hESCs."
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sparser
"Furthermore, we demonstrated that USP3 and Oct4 interact regardless of whether Oct4 is endogenously or exogenously expressed and co-localize in the nuclei of hESCs ( xref )."
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sparser
"Thus, the interaction between USP3 and Oct4 is critical for maintenance of the pluripotency of hESCs."
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