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MYSM1 activates gene expression. 2 / 2

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"9 One of the main known MYSM1 substrates is histone H2A, monoubiquitinated at K119, and MYSM1 catalytic activity on this epigenetic mark promotes the activation of gene expression."

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"Monoubiquitination of H2A on lysine 119 (H2AK119Ub) represses transcription, and MYSM1 catalyzes removal of this ubiquitin moiety to initiate gene expression."

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IndraLab

Statements

MYSM1 activates gene expression. 2 / 2

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