IndraLab

Statements

USP25 deubiquitinates FOXM1. 4 / 4
| 4
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"HDACi treatment increased the ubiquitination level of FOXM1 by suppressing ubiquitin-specific peptidase 21 (USP21), which deubiquitinates FOXM1."
34335925
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"FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal like Breast Cancer."
30865895
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"Similarly, USP21 WT, but not USP21 C221A, immunopurified from 293T cells reduced polyubiquitination of FOXM1 isolated from proteasome inhibitor treated 293T cells in an in vitro deubiquitination assay (XREF_SUPPLEMENTARY)."
30865895
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"USP21 increases the stability of FOXM1, and USP21 binds and deubiquitinates FOXM1 in vivo and in vitro, indicating a direct enzyme-substrate relationship."
30865895