IndraLab

Statements


USP7 deubiquitinates SPRTN. 6 / 6
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"USP7 deubiquitinase deubiquitinates SPRTN upon DPC induction, antagonizing the autocatalytic cleavage and subsequent inactivation of SPRTN."

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"Upon DPC induction, SPRTN is deubiquitinated by USP7, promoting SPRTN stability."

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"Upon formaldehyde treatment and other yet to be identified signals, SPRTN is deubiquitinated by USP11 (this study), USP7, and VCPIP1."

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"USP7 deubiquitylates SPRTN upon DPC induction."

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"Recently, it was shown that USP7 deubiquitinates SPRTN, preventing SPRTN auto-cleavage upon DPC induction."

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"showed that deubiquitination of SPRTN by USP7 does not govern SPRTN localization on chromatin."