IndraLab

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USP35 deubiquitinates STING1. 5 / 5
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"In ovarian cancer, USP35 deubiquitinates STING and affects STING-mediated interferon signaling 34."
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"For example, USP35 promotes ovarian cancer development by deubiquitinating and inactivating STING [34]."
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"Zhang et al. reported that USP35 directly interacts with STING and deubiquitinates STING."
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"In ovarian cancer, USP35 can directly deubiquitinate and inactivate the stimulator of interferon genes protein, decreasing the sensitivity of tumor cells to cisplatin (16)."
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"Our data further showed that USP35 can directly deubiquitinate and inactivate STING."
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