IndraLab

Statements

Paracetamol inhibits KCNK18. 3 / 3
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"Acetaminophen, ibuprofen, nabumetone, and bupropion inhibited TRESK, but had no effect on TREK-2."
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"As shown in Fig. 1, acetaminophen (100 µM), ibuprofen (100 µM), and nabumetone (100 µM) inhibited TRESK by 27±7%, 21±9%, and 32±11%, respectively, but they did not affect TREK-2."
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"The IC for inhibition of TRESK by acetaminophen, ibuprofen, and nabumetone was 220±26 µM, 889±10 µM, and 557±35 µM.Antidepressants used in this study, except bupropion, inhibited both TREK-2 and TRESK currents."
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