The INDRA Database

reach

"As in the above studies, the LPS induced activation of TAK1 and IKK were both markedly reduced and delayed in Dream -/- cells compared with WT (XREF_SUPPLEMENTARY)."

24487321

➶

reach

"The levels of M2 microglia‐related anti‐inflammatory cytokines (IL‐4, IL‐10 and Arg‐1) were decreased by LPS stimulation but increased after treatment with TAK‐242, JSH23, and ferulic acid (Figure 4B; p < 0.05)."

36601662

➶

reach

"LPS-induced activation of TAK1, an upstream regulator of NF-kappaB and MAPK pathways, was significantly inhibited by RRx-001 pretreatment, whereas recruitment of MyD88 to TLR4 was not affected by RRx-001."

35462935

➶

reach

"4 '-HW suppressed LPS induced degradation of IkappaB-alpha and activation of IKK and TAK in RAW 264.7 macrophages."

28792498

➶

reach

"Our present studies showed that CD200Fc elicited an obvious inhibitory effect of p-ERK1/2, p-p38, and p-JNK in LPS-induced hRPTECs.Stimulation of the TLR4 extracellular domain by LPS sequentially trig[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

25791482

➶

reach

"We further found that LPS induced degradation of IRAK1 and phosphorylation of TAK1 were markedly inhibited in a berterion concentration dependent manner without changes in the levels of TLR4, MyD88, or TAK1 (XREF_FIG A)."

25393510

➶

reach

"Hoechst staining of RSC96 cells revealed that LPS induced nuclear apoptosis (Figure 3A), and a TLR4 inhibitor (TAK‐242) and NF‐kB inhibitor (JSH23) reversed this trend (Figure 3A1; p < .05)."

35499270

➶

reach

"Then, we found that Fpr2 inhibition markedly reduced the activation of transforming growth factor beta activated kinase 1 (TAK1) induced by LPS."

32106380

➶

reach

"USP18 alleviated LPS induced sepsis by inhibiting TAK1 activity."

34235538

➶

reach

"USP18 alleviated LPS induced sepsis by inhibiting TAK1 activity."