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COPS5 inhibits AP1. 3 / 3
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"We have demonstrated that CARP repressed JAB1 mediated AP-1 activation and enhanced p27 nuclei accumulation XREF_BIBR."

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"As is shown in Fig. 9, group 1 that is transfected with AP-1-Luciferase and pCMV-Myc vector showed nearly no activity of the luciferase reporter, while overexpression of c-jun (group 2) and Jab1 (grou[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The cotransfection of HBx and Jab1 resulted in substantial activator protein 1 (AP-1) activation and knockdown of endogenous Jab1 attenuated AP-1 activation caused by HBx."