IndraLab

Statements

COPS5 activates TWIST1. 3 / 3
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"Moreover, CSN5 silencing inhibited the secretion of TGF-beta, IL-1beta and IL-6 and the transcriptional activity of transcription factor NF-kappaB and Twist in human colorectal cancer cells."
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"This finding suggests that Jab1 together with TGF-β1 may mediate a relevant signaling pathway in CRS and NP."
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"However, it is unknown how Jab1 can modulate the inflammation in CRS and nasal polyposis."
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