IndraLab

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"In the in vivo metastasis assay, USP36 overexpression significantly enhanced the lung metastasis of ECA109 cells (Fig. 4I)."
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"In the in vivo metastasis assay, USP36 depletion significantly reduced lung metastasis in ECA109 cells (Fig. 3I)."
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"Our previous study clarified that ubiquitin-specific peptidase 36 (USP36) accelerates ESCC proliferation and metastasis through stabilizing YAP protein [13]."
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"USP36 contributes to the tumor stemness, growth, Oxa-resistance, and metastasis of colon cancer in xenograft models."
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"Taken together, these results suggested that USP36 promotes proliferation and metastasis in CRC through stabilizing RBM28.Next, we evaluated whether USP36/RBM28 exerts its oncogenic effects through the p53 signaling pathway."
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"The analysis on liver metastasis murine revealed that the overexpression of USP36 caused a promotion of the liver metastasis of HCT116 cells (Figure 3F)."
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