IndraLab

Statements



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"The results showed that Ataxin-3 promoted testicular cancer cell proliferation by inhibiting PTEN and indirectly activating the AKT/mTOR signaling pathway.From January 2012 to October 2017, 53 pairs o[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"It was found that ataxin-3 knockdown suppressed cell proliferation and invasion."

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"We conjectured that upregulated HRH1 and ATXN3 were targeted by both piRNAs and miRNAs, and along with BRAF and CCND1 might induce cell proliferation in GBM through G-protein-coupled receptor or Akt signalling pathways due to downregulation of the respective targeting small RNAs."

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"In addition, ATXN3 depletion significantly decreased PC cell proliferation, invasion and stem-like properties."

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"Therefore, these results suggest that ATXN3 positively regulates the protein level of EIF5A2 in ATCs.To further investigate whether ATXN3 mediates the proliferation of ATCs by regulating EIF5A2, we up[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The results showed that overexpression of ataxin-3 promoted the proliferation of TCam-2 and I-10 cells ( Fig. 2 C and D)."

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"53 However, a potential function for HCC may be derived from testicular cancer where ATXN3 overexpression enhanced cell proliferation, and ATXN3 knockdown inhibited cell proliferation."

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"As shown in Fig. 4 b, the CCK-8 assay data demonstrated that overexpression of EIF5A2 markedly enhanced the proliferation of SW1736 cells, and knockdown of ATXN3 reversed the enhanced proliferation in[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Then, we overexpressed exogenous Ataxin-3 in TCam-2 and I-10 cells and found that Ataxin-3 promoted cell proliferation significantly."

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"Our results showed that Ataxin-3 overexpression promoted TC cell proliferation."

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"Finally, ATXN3 could promote tumor proliferation, invasion and stem-like properties of prostate cancer through YAP."

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"Ataxin-3 is overexpressed and promotes cell proliferation in both NSCLC and testicular cancer."

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"Knockdown of ATXN3 significantly inhibited tumor proliferation, invasion and stem-like properties."

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"Moreover, our results indicated that ATXN3 promotes ATC proliferation and metastasis in vitro."

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"ATXN3 promoted the proliferation, migration, invasion, and tumorigenic ability of HCC in vitro and in vivo."

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"Then, we demonstrated that ATXN3 can promote the proliferation and metastasis of ATC cells in vivo and in vitro."

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"In addition, the protein level of EIF5A2 was also significantly consistent with the protein level of ATXN3 in clinical ATC tissues, while the mRNA expression level of ATXN3 was not consistent with the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Increased ATXN3 expression dramatically promoted cell proliferation, migration, and invasion."