IndraLab

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USP34 deubiquitinates NFIC. 5 / 5
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"USP34 deubiquitinates and stabilizes NFIC."

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"Mechanically, we demonstrated that USP34 deubiquitinates and stabilizes NFIC during odontoblast differentiation."

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"To test whether USP34 dependent deubiquitination of NFIC is involved in odontogenic differentiation of DPCs, DPCs were infected with Lv-NFIC, or Lv-GFP as control."

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"XREF_BIBR, XREF_BIBR Our research identified that USP34 deubiquitinates and stabilizes NFIC to promote odontoblast differentiation and thus regulates root formation."

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"Ubiquitination assay showed increased ubiquitination level of NFIC in USP34 deficient 293T cells, indicating the presence of USP34 dependent deubiquitination of NFIC."