IndraLab

Statements

6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine decreases the amount of USP9X. 3 / 3

| 3

reach

"Taken together, BIX-01294 decreases the expression of USP9X and promotes the degradation of MCL1, which eventually leads to apoptosis in bladder cancer cells."

25685062

➶

reach

"We found that BIX-01294 reduced the level of USP9X in the dose- and time dependent manner, and MCL1 was degraded more in USP9X siRNA knockdown cells compared with the Control siRNA knockdown cells."

25685062

➶

reach

"We found that BIX-01294 up-regulated the expression of PMAIP1 and down-regulated the level of MCL1 and USP9X."

25685062

IndraLab

Statements

6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine decreases the amount of USP9X. 3 / 3

INDRA sources:

Databases

Reading