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TP53 bound to RITA1 activates mutated TP53. 1 / 1

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"Using fluorescence anisotropic experiments, it was shown that RITA directly binds p53 and causes a conformational change that prevents the binding between p53 and MDM2, effectively inducing apoptosis in cells with wild-type p53, but not mutant p53 or null."

24756955

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IndraLab

Statements

TP53 bound to RITA1 activates mutated TP53. 1 / 1

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