IndraLab

Statements

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"In addition, USP15 overexpression reversed the inhibited proliferation and migration ability of glioma cells induced by GINS1 silencing in U251 cells, whereas USP15 knockdown impaired the elevated proliferation and migration ability of glioma cells induced by GINS1 overexpression in A72 cells."
36065190
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"However, in Huh1 and HA22T cell lines, overexpression or knockout USP15 does not change the apoptosis rate of the two cell lines (Figure S5), which indicated that a high level of USP15 represses the proliferation of these cell lines."
36900163
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"Loss of Usp15 significantly increased proliferation of these KC cells (Fig. 2e), while it did not affect KPC cells (Supplementary Fig. 3e), presumably, because those cells are at the maximal proliferation rate."
38902237
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"USP15 overexpression inhibits cell proliferation and growth in soft agar."
29299163
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"In line with its haploinsufficient tumorigenic effect, heterozygous loss of Usp15 also significantly increased proliferation and sensitized to Olaparib treatment, but not as pronounced as complete Usp15 loss (Supplementary Fig. 4e and f)."
38902237
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"In addition, apoptosis induction and proliferation inhibition can be caused by downregulation of USP15 expression."
35924961
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"Whereas, knock-down of USP15 dramatically inhibited tumor cell proliferation evidenced by CCK8 and colony formation assays, within K1 and 8505 C, which both represent BRAF -mutated thyroid cancer cells [K1 represents PTC cells, 8505 C represents ATC cells] (Fig. 3a, b, Supplementary Fig. 2d−f)."
38750011
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"Notably, Fukushima et al. (2017) suggested that USP15 could inhibit the proliferation of the PCa cell line (PC-3)."
36811009