IndraLab

Statements

EGF binds AREG and EGFR. 5 / 5
| 5
sparser
"For example, Areg and EGF specifically interact with the EGF receptor to promote the growth of normal epithelial cells [ xref ], which may partially explain the prolonged ductal tree extension."
25853264
sparser
"Several ligands, such as EGF and amphiregulin, bind to EGFR, whereas there is no known high-affinity ligand binding to Her-2."
12915878
sparser
"Inasmuch as we normalized the concentrations of AR and EGF to similar levels of phosphorylation of EGFR, we did not further investigate the stability of AR-EGFR and EGF-EGFR binding in intracellular vesicles."
19173594
sparser
"For example, the concomitant presence of the epidermal growth factor receptor (EGFR) and its ligands EGF and amphiregulin is associated with enhanced tumor aggressiveness and shorter survival in patients. xref K-ras proto-oncogene and mutations of the p53 tumor-suppressor gene and the Smad4 gene are frequently dysregulated in the tumors."
20224296
sparser
"Monoclonal antibodies directed against the EGF receptor show differential bindings of amphiregulin and EGF to the EGF receptor."
21533382