IndraLab

Statements

OTUD4 inhibits AKT. 3 / 3
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"Akt pathway activity repressed by HIN-1 was enhanced in HIF-2alpha-deficient human NSCLC cells and xenografts [XREF_BIBR]."
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"Expression of HIN-1 also inhibits Akt mediated retention of p27 in the cytoplasm."
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"The expression of OTUD4 is significantly down-regulated in various solid tumor tissues, and the upregulation of OTUD4 impedes the proliferation, migration, and invasion of liver, breast and lung cancer cells by suppressing AKT pathway [32]."
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