IndraLab

Statements

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"Ubiquitin specific protease 14 (USP14) promotes proliferation and metastasis in pancreatic ductal adenocarcinoma."
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"30 Overall, these data suggest that increased expression of Usp14 may enhance beta-catenin-mediated transformation of normal colon cells, but not metastasis of malignant colon cancer cells."
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"In addition, depletion of USP14 led to proteasome-dependent degradation of TAZ and ultimately arrested PDAC tumour growth and liver metastasis."
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"In contrast, studies using OSCC cells have demonstrated that TGF-beta signals can mediate Epithelial- mesenchymal transitions, further contributing to cancer cells migration and invasion (Meng et al.,[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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