IndraLab

Statements

USP22 increases the amount of ZEB1. 5 / 5
| 5
reach
"USP22 depletion or USP22 deubiquitinase inactive mutant USP22 (m) enhanced the ubiquitination level of ZEB1 (Fig. 4H, I)."
36906615
reach
"Thus, analysis of novel co-regulator for modulation of ZEB1 action may provide the effective strategy for anti-angiogenic therapy resistance in HCC.In this study, our results have demonstrated that USP22 up-regulates ZEB1-mediated VEGFA transcription."
36906615
reach
"Upregulation of USP22 can increase the expression of the ZEB1 and Snail transcription factors, significantly reduce the expression of E-cadherin at cell–cell junctions, and upregulate the expression of mesenchymal markers [143]."
36902253
reach
"Our results showed that ectopic expression of USP22 increased ZEB1 protein expression and USP22 deletion reduced ZEB1 protein expression, while USP22 had no obvious effect on mRNA expression of ZEB1 in HCC-derived cell lines (Fig. 4A–C)."
36906615
reach
"Ectopic expression of USP22 did not increase the protein expression of ZEB1 in the presence of ubiquitin proteasome inhibitor MG132."
36906615