IndraLab

Statements


USP4 activates AKT. 3 / 3
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"AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by smurf2 and deubiquitinating enzyme USP4."

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"These data implied that Akt mediated MMT in PD via Smurf2 modulation and and or Smad7 degradation while conceivably maintaining the TbetaRI stability, most likely by the USP4."

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"The deubiquitinating enzyme USP4 modulates AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis (Xiao et al., 2015)."