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USP13 inhibits pathogenesis. 2 / 2
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"Collectively, our above findings confirm that USP13 is a strong blocker of NASH pathogenesis and its related metabolism dysregulation in mice.3.5 USP13 alleviates NASH pathogenesis by repressing IRHOM2-MAP3K7 signal cascade."
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"To explore the mechanism of attenuated virulence caused by usp13 deletion, we examined the effect of usp13 mutation on the ability to block activation of host phagocytes."
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