IndraLab

Statements

sparser
"KCNMA1 directly interacts with the alpha subunit of CACNA1C channel xref leading to Ca2+ influx, opening of KCNMA1 channel, and efflux of the intracellular K+."
20830292
sparser
"Vascular MaxiK are formed by the pore-forming alpha subunit and the modulatory beta1 subunit, which imprints unique kinetics, Ca2+/voltage sensitivities and pharmacology to the channel."
15272033
sparser
"To our knowledge in bladder smooth muscle the BK channel pore forming alpha subunit BKalpha associates in homotetramers with 4 regulatory smooth muscle specific beta1 subunits."
19447431
sparser
"The BK channel in vascular smooth muscle is formed by an ion-conducting alpha subunit and a regulatory beta(1) subunit, which couples local increases in intracellular Ca(2+) to augmented channel activity and vascular relaxation."
15057310