IndraLab

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Dorsomorphin inhibits NLRP3. 4 / 4
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"In conclusion, compound C was shown to significantly attenuate the NLRP3 inflammasome despite AMPK knockdown, rendering it as the novel target of compound C. Potentially, compound C attenuates NLRP3 inflammasome through the suppression of mitochondrial ROS production."
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"However, compound c, an inhibitor of AMPK, suppressed HSYA-induced inhibition of the NLRP3 inflammasome, indicating the essential role of AMPK signalling in regulating inflammasome activity.In additio[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Interestingly, compound C significantly attenuated the activation of NLRP3 inflammasome."
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"Compound C attenuates NLRP3 inflammasome despite AMPK knockdown in LPS plus palmitate induced THP-1 cells."
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