IndraLab

Statements

USP15 binds TUT1. 13 / 13
6 | 1 6
reach
"Previously, we found that SART3 serves as a scaffold to strengthen the binding between USP15 and TUT1, and SART3 deletion mutant attenuates this binding [ 1 ]."
38310689
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"Moreover, inhibition of the USP15-TUT1 cascade triggered mild and chronic endoplasmic reticulum (ER) stress."
32839293
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"These findings provide a possibility that disturbance of the USP15-TUT1 cascade may induce chronic and mild ER stress, leading to an acceleration of neurodegenerative phenotype."
32839293
biogrid
No evidence text available
19615732
biogrid
No evidence text available
33961781
sparser
"Because the USP15-TUT1 axis is crucial for regulating U6-snRNA stabilization [ 1 ], we speculated that USP4 regulates TUT1 via deubiquitination, as does USP15 ( Fig. 2 B)."
38310689
sparser
"We presumed that SART3 regulates the binding of USP4 with TUT1 similar to the USP15-TUT1 interaction."
38310689
biogrid
No evidence text available
28276505
sparser
"Because this mutant also suppresses the interaction of USP15 with TUT1 [ 1 ], we assumed that overexpression of SART3 affects endogenous USP15 rather than USP4."
38310689
biogrid
No evidence text available
32839293
biogrid
No evidence text available
32839293
sparser
"Intriguingly, unlike in the case of USP15-TUT1, we did not observe a strong binding between USP4 and TUT1 in the presence of SART3."
38310689
biogrid
No evidence text available
32839293