IndraLab

Statements


OTUB1 activates PTK2. 3 / 3
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"Therefore, OTUB1 significantly increased multiple oncogenes expression and activated PI3K/AKT and FAK/ERK signaling in a RACK1-dependent manner in HCC."

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"Immunoblotting showed that OTUB1 overexpression enhanced RACK1 and led to the activation of the Akt and ERK/FAK pathways in HCC cells."

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"OTUB1 contributed to HCC progression by activating PI3K/AKT and FAK/ERK signaling in a RACK1-dependent manner."