IndraLab

Statements

COPS5 inhibits PTEN. 3 / 3
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"Interestingly,Jab1 knockdown increased PTEN protein half-life, resulting in increased PTEN expression."
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"Jab1 knockdown produced anti-proliferative and anti-migratory effects in BTC cells by increasing DNA damage, stabilizing PTEN, and leading to G1 cell cycle arrest."
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"In cycloheximide chase assays, Jab1 silencing increased the half-life of PTEN protein compared with the control in SNU478 and HuCCT-1 cells (Fig. 4B)."
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