IndraLab

Statements


USP11 inhibits ARID1A. 2 / 2
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"Conversely, the deubiquitinase USP11 has been shown to inhibit squamous cell carcinoma by stabilizing ARID1A protein through its interaction with syndecan‐2 (SDC2)."

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"TRIM32 depletion inhibits SCC cell proliferation, metastasis, and chemoresistance by stabilizing ARID1A, while USP11 depletion promotes SCC development by promoting ARID1A degradation."