IndraLab

Statements


USP15 deubiquitinates SMAD2. 1 / 1
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"reports have suggested that USP15 acts as a key regulator of TGF-b receptor-signaling pathways by deubiquitinating the TGF-b receptor itself and its downstream transducers receptor-regulated SMADs (R-SMADs), including SMAD1, SMAD2, and SMAD3, thus activating the TGF-b target genes."