IndraLab

Statements

TLR increases the amount of USP18. 3 / 3
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"These results indicate that USP18 expression can be induced by TLR induced signaling pathways, which, in turn, can suppress TLR mediated NF-kappaB activation to form a negative feedback loop."
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"Furthermore, TLR ligands, LPS, Pam3CSK4 and CL097 all gave the same result of increased mRNA level of USP18, supporting that TLR-induced signaling pathway induces USP18 expression [42]."
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"Other TLR ligands, such as Pam3CSK4 (TLR2 ligand) or CL097 (TLR7/8 ligand), could also induce USP18 expression in THP-1 cells (XREF_FIG)."
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