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USP39 deubiquitinates CHEK2. 3 / 3
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"Mechanistically, USP39 deubiquitinates and stabilizes CHK2, which in turn enhances CHK2 stability."
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"Mechanistically, <span class="match term0">USP39</span> deubiquitinates and stabilizes <span class="match term1">CHK2</span>, which in turn enhances <span class="match term1">CHK2</span> stability"
30771428
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"Additionally, USP39 deubiquitinates and stabilizes CHK2 in lung cancer, and the knockdown of USP39 compromises G2/M checkpoint, thereby conferring decreased apoptosis and resistance to chemotherapy and radiotherapy [114]."
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