IndraLab

Statements

Capsaicin inhibits ITCH. 6 / 6
| 6
reach
"Repeated application of topical capsaicin causes depletion of SP from sensory nerve endings and abolishes pain and itch (Fitzgerald, 1983; Wallengren and Moller, 1986; Lynn, 1992)."
11553396
reach
"In addition, creams containing local anesthetics [XREF_BIBR], capsaicin, doxepin [XREF_BIBR], strontium nitrate [XREF_BIBR], or nedocromil sodium [XREF_BIBR] can be helpful to relieve itch."
26064156
reach
"With repeated topical applications, capsaicin not only reduces the magnitude of chemically evoked itch and nociceptive sensations [XREF_BIBR] but also attenuates the itch mediated by an intradermal injection of histamine and abolishes the itch elicited by cowhage [XREF_BIBR]."
19423224
reach
"To ablate the TRPV1- and TRPV1- and TRPA1-positive sensory neurons, we used the super potent capsaicin analogue resiniferatoxin (RTX), which has been shown to suppress acute pain and itch in animal models via axonopathy."
28745101
reach
"Itch evoked by cowhage or histamine is reduced or blocked by capsaicin desensitization, suggesting that pruriceptive neurons are capsaicin sensitive."
19423224
reach
"Topical Capsaicin in Poly(lactic-co-glycolic)acid (PLGA) Nanoparticles Decreases Acute Itch and Heat Pain."
35563669