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OTUB1 activates ATF6. 2 / 2
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"Our results indicate that high OTUB1 expression promotes bladder cancer progression by stabilizing ATF6 and that OTUB1 is a potential therapeutic target in bladder cancer."

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"It has been found that OTUB1 can stabilize activating transcription factor 6α (ATF6α) in response to endoplasmic reticulum stress and promote bladder cancer progression (122)."