IndraLab

Statements

Capsaicin inhibits KCNH2. 3 / 3
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"The data presented in this study show that capsaicin blocks hERG, and that this blockade is conspicuously enhanced by the mutation Y652A but not significantly affected by the mutation F656A."
19903464
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"The precise mechanism by which capsaicin blocks hERG requires further investigation."
19903464
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"XREF_BIBR found that capsaicin, a pungent irritant occurring in peppers, enhances hERG block upon mutation of Y652A 4-fold, while F656 was suggested to be relatively unimportant for block."
22194911