IndraLab

Statements

SCN5A binds FOXO1. 5 / 5
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"Foxo1 binds the promoter region of SCN5A [ xref ], and exogenous Foxo1 expression decreases SCN5A promoter activity in HL-1 cells [ xref ]."
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reach
"Foxo1 directly binds SCN5a promoter."
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sparser
"Foxo1 directly binds SCN5a promoter."
22400069
reach
"Foxo1 binds the promoter region of SCN5A [XREF_BIBR], and exogenous Foxo1 expression decreases SCN5A promoter activity in HL-1 cells [XREF_BIBR]."
25781322
sparser
"To confirm the association of Foxo1 with the SCN5a promoter region including IREs, a ChIP assay was carried out in HL-1 cells and mouse ventricular myocytes, and it unveiled a clear enrichment of DNA amplified by PCR with two sets of primer pairs flanking Foxo1 binding IREs ( 5′-CAAAACAAAACA-3′ ) in the proximal SCN5a promoter region following immunoprecipitation with Foxo1 antibody, but not with IgG control ( xref )."
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