IndraLab
Statements
Hydroxychloroquine increases the amount of TNF. 2 / 2
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"22 Several mechanisms have been evoked to explain the chloroquine/hydroxychloroquine-induced inhibition of TNF␣ production by monocyte-macrophages: disruption of cellular iron homeostasis, 23 inhibition of TNF␣ mRNA expression, 20 inhibition at a pretranslational stage by a non-lysosomotropic mechanism, 24 or at a post-translational stage by blocking the conversion from cell-associated pro-TNF␣ to a soluble mature form."