IndraLab

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OTUD6B decreases the amount of IRF3. 2 / 2

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"Our results showed that overexpression of OTUD6B, and not defective OTUD6B-C57S, dramatically attenuated the ubiquitination levels of exogenously expressed IRF3, demonstrating that OTUD6B does reduce IRF3 ubiquitination levels and its deubiquitinase activity is critical (Fig. 5C)."

37650650

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"In contrast, OTUD6B knockdown enhanced IRF3 ubiquitination modification levels (Fig. 5D)."

37650650

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IndraLab

Statements

OTUD6B decreases the amount of IRF3. 2 / 2

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