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CYLD inhibits NFAT. 2 / 2
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"Our findings suggest the following scenario : PKCtheta and beta are the essential kinases in a physiological signaling cascade that is necessary to counteract CYLD mediated repression of NFkappaB and NFAT transactivation."
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"Next, we further verified that Cyld inhibited B cell proliferation and augmented B cell apoptosis in miR-130b overexpressed mice.The downstream of BCR signaling consists of NFAT, NF-κB and ERK pathway[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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