IndraLab

Statements

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"The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metastasis through Hippo signaling pathway."
36813921
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"UCHL3 stimulates metastasis of gastric cancer through upregulating IGF2."
34278751
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"Collectively, UCHL3 can promote cancer progression and metastasis, indicating that UCHL3-specific inhibitors may have great therapeutic potential in HNSCC (152)."
40337608
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"GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer."
38664501
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"UCHL3 promotes cervical cancer development and metastasis by stabilizing NRF2 via deubiquitination."
36527747
eidos
"UCHL3 promotes cervical cancer development and metastasis by stabilizing NRF2 via deubiquitination ."
36527747
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"Our findings showed that knockdown of UCHL3 inhibited cell growth, migration and invasion in cervical cancer cells while UCHL3 knockdown inhibited cervical cancer development and metastasis in vivo in mouse models."
36527747
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"In cervical cancer studies, it has been found that UCHL3 promotes the development and metastasis of cervical cancer by stabilizing NRF2 through deubiquitination [120]."
40258841
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"Collectively, our findings suggest that UCHL3 promotes cervical cancer development and metastasis by stabilizing NRF2 via deubiquitination."
36527747
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"Therefore, we propose that the inhibition of UCH-L3 activity after anti-cancer therapy could suppress tumor remodeling and metastasis, providing a new strategy to improve the prognosis of gastric cancer patients."
37460253
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"UCHL3 increases the stability of the YAP protein in a deubiquitinating activity-dependent manner, thereby promoting the progression and metastasis of anaplastic thyroid cancer [27]."
38474064
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"UCHL3 depletion significantly decreased ATC progression, stem-like and metastasis, and increased cell sensitivity to chemotherapy."
36813921