IndraLab

Statements

Temozolomide inhibits NFKB1. 4 / 4
| 1 3
eidos
"As with U87 cells , TMZ blocked p50 and induced p53 recruitment in cells expressing p50wt ( Figure 4C , left panel ) ."
30940658
reach
"The mechanism by which TMZ reduces NFkB activity in glioma cells is still poorly understood."
26520369
reach
"DHT and TMZ synergistically reduce cancer cell viability, NFkB activity, and markedly halt cell cycle progression."
30399573
reach
"However, the observation that similar levels of gammaH2AX foci are induced in wt and p50 depleted cells by TMZ (XREF_FIG) suggests that the resistance to cytotoxicity with loss of p50 is not due to decreased DSB formation or increased DSB repair."
22152481