IndraLab

Statements

USP7 activates E3_Ub_ligase. 4 / 4
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"This result indicates that Usp7 augments the E3 enzymatic activity of RAUL."
21167755
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"40 HAUSP modulates the stability of three E3 ligases, including RING finger protein 168 (RNF168), 74 to regulate histone H2A and participate in Ub dependent DNA damage signaling."
29967688
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"Inhibition of USP7 could degradate oncogenic E3 Ub-ligase MDM2, and reactivate tumor suppressor p53."
37795365
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"Whereas, USP7 accelerates p14ARF degradation by stabilizing its E3 ligase TRIP 12 and promotes the progression of hepatocellular carcinoma [48] ."
28216017