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USP2 inhibits glucose. 2 / 2
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"USP2 deficiency in the liver also perturbs normal diurnal glucose rhythms under restricted feeding conditions."

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"For example, USP2 in ventromedial hypothalamic neurons attenuates aberrant increases in blood glucose by mitigating glycogenolysis in the liver, whereas hepatic USP2 regulates gluconeogenesis and diurnal glucose metabolism in the liver [28,31]."