IndraLab

Statements


USP18 inhibits IL2. 4 / 6
| 1 3

eidos
"Taken together , USP18 downregulates IL-2 synthesis and TCR-induced T cell proliferation [ 43 ] ."

reach
"Genetic depletion of USP18 causes NF-κB and NFAT hyperactivation and hyperproduction of IL-2 in T cells [154]."
| PMC

reach
"To understand the molecular mechanisms by which USP18 reduces IL-2 production in T cells, we first examined the activation of TCR proximal signaling events."

reach
"Taken together, USP18 downregulates IL-2 synthesis and TCR induced T cell proliferation [XREF_BIBR]."