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3D binds PRPF8. 2 / 2
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"For example, 3D polymerase from enterovirus 71 directly binds to pre-mRNA processing factor 8 (PRPF8) and disrupts the pre-mRNA splicing processes, contributing to the invasion of the virus (Liu et al., 2014)."
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"In the case of picornaviruses, it has been shown recently that the viral polymerase 3D binds to PRPF8, a core components of U5, and blocks mRNA maturation, with the consequent accumulation of the lariat intermediate [XREF_BIBR]."
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