IndraLab

Statements

HMOX1 binds IL10 and IL10RB. 2 / 2
| 2
sparser
"Epistatic interaction of the IL-10 gene with the IL-10 signaling pathway genes, IL10RB and HO1, in pediatric IBD."
28785144
sparser
"The specific findings include the following: (1) IL-10 rs3024496 is identified to be associated with pediatric IBD; (2) an aa interaction was found between IL-10 SNPs rs3024496 and rs1800872; (3) the SNP-SNP interaction in the IL-10 gene affects its action with the IL-10 receptor IL10RA ; (4) the IL-10 signaling pathway genes IL10RB and HO1 together are significantly associated with pediatric IBD via SNP-SNP interaction; and (5) a significant association of the three genes, IL-10 , IL10RB and HO1 , with pediatric IBD was identified from epistatic interaction analysis among three SNPs."
28785144