IndraLab

Statements


HSPA binds KCNH2 and HSP90. 3 / 3
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sparser
"It could be that hypoxia inhibits Hsp90 binding to hERG by reducing steady state expression levels of endogenous Hsp90 and/or Hsp70."

sparser
"Both HSP70 and HSP90 directly interact with hERG (the human ether-á-go-go-related gene) whose disorders can lead to long-QT syndrome and sudden cardiac death [ xref ]."

sparser
"Mutations such as R752W and G601S strengthen the interaction of hERG with Hsp70 and Hsp90."