IndraLab

Statements



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"For example, it is known that transcription levels of Kv1.5 are modulated by glucocorticoids, that Kv3.4 expression is upregulated by skeletal muscle innervation, and that PKA phosphorylation at the surface of the ER augments hERG biosynthesis."

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"ER retention of hERG 125kDa form by CH was due to defective trafficking and was rescued by exposing cells to hypoxia at low temperatures or treatment with E-4031, a hERG channel blocker."