IndraLab

Statements

UCHL1 inhibits translation. 3 / 3
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"The circular RNA circular RNA sponge for miR-7 (ciRS-7) inhibits the expression of UCHL1 to promote APP and BACE1 degradation by inhibiting the translation of NF-κB and inducing its cytoplasmic localization (Shi et al., 2017)."
39281280
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"For example, the embedded invSINEB2 element of the lncRNA AS Uchl1 regulates AS Uchl1 nuclear retention and consequently inhibits AS Uchl1-enhanced translation of the sense protein-coding Uchl1 mRNA by recruiting IL enhancer-binding factor 3 (ILF3) [46]."
35067197
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"Under cap dependent translation inhibition due to stress, UCHL1 lncRNA moves from the nucleus to the cytoplasm, binds to Uchl1 mRNA and allows its cap independent translation."
23887658