IndraLab

Statements



reach
"The depletion and pharmacological inhibition of USP9X by WP1130, an inhibitor of USP9X, downregulate endogenous Snail1 protein, inhibit cell migration, invasion, metastasis, and increase cellular sensitivity to cisplatin and paclitaxel both in vitro and in vivo, whereas the reconstitution of Snail1 in cells with USP9X depletion at least partially reverses these phenotypes."

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"Proliferation, migration and invasion of osteosarcoma cells were inhibited by down-regulation of USP9X, and were related to the ERK1/2 and PI3K/Akt signaling pathways, therefore, it might probably become a new target for the prevention and treatment of osteosarcoma."

sparser
"The invasided cell numbers were reduced after the overexpression of FAM3D-AS1, suggesting that FAM3D-AS1 can inhibit the cell invasion ( xref E), Thus, these results revealed that FAM3D-AS1 possessed the function of inhibition of cell proliferation and invasion."

sparser
"Enforced expression of FAM198B inhibited cell invasion, migration, mobility, proliferation and anchorage-independent growth and FAM198B silencing exhibited opposite activities in vitro."

reach
"Knockdown of endogenous USP9X expression evidently inhibited the migration and invasion of PANC-1 cells, and promoted cell apoptosis."

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"Cell migration and invasion were significantly inhibited by down-regulation of USP9X."